Originally published in Medscape Filippo Beleggia, MD, PhD, didn’t believe his own data. As a postdoctoral researcher, he spent years in the laboratory of Christian Reinhardt, MD, PhD, at the University Hospital Cologne, Cologne, Germany, screening genes in mice genetically engineered to develop small cell lung cancer (SCLC), hunting for the drivers of one of medicine’s […]

Originally published in Medscape People with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) wake up every morning to relentless abdominal pain — the kind that makes ordinary activities feel impossible. The pain isn’t just physical; it’s isolating, invisible to others, and exhausting in its constancy. For years, scientists suspected that gut bacteria played a

For over a century, the hallmark of Parkinson’s—Lewy bodies—has been an enigma. Why do some patients with many have mild symptoms, while others with few are devastated?

We may have been looking at the wrong culprit.

I dive into a breakthrough discovery of nanoscale protein clumps, alpha-synuclein oligomers, that were hiding in plain sight. A new imaging technique finally allows researchers to see them in human brains, and what they found is a complete surprise.

The brain protects itself with a fascinating ‘sugar shield,’ but this defense weakens as we age. I delve into the groundbreaking research that could turn this shield into a powerful therapeutic target in the fight against cognitive decline and neurodegenerative diseases.